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What makes astaxanthin special is that it can cross cell membranes because it contains both a fat-soluble and a water-soluble component

This is mechanistically relevant for Crohn's disease, where perianal and enterocutaneous fistulas are a major source of morbidity

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for the fasted-morning option, the dose goes in before the first food of the day, with breakfast held until the post-dose window has passed