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Description

While AOD-9604 is structurally derived from hGH, it differs significantly in its receptor binding profile and downstream signaling activity

The research rationale established by NNMT-knockdown studies in diet-induced-obese mice is that inhibiting NNMT preserves intracellular NAD+ and SAM levels, which in adipocyte (fat-cell) models has been shown to suppress de novo lipogenesis