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Vitamin B12 injection effects can include: Soreness or slight bruising where the needle goes in A warm feeling right after the injection Mild headache in some people, which usually passes quickly Rare allergic reactions, which is why a health check happens first Vitamin B12 injection painful is a common worry, but most people describe it as a quick pinch rather than anything severe

The answer depends on several factors, including the cause and severity of deficiency, your overall health, and how long symptoms have been present

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Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults