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This upregulation of miR-449a inhibits the expression of its target gene ACSL4, thereby suppressing neuronal ferroptosis (139)

Sirtuin 3 as a regulator of oxidative stress Sirtuin 3 is an NAD + -dependent deacetylase that plays a role in mitochondrial metabolic processes, including energy production, oxidative stress, the tricarboxylic acid cycle, and other processes (Bause et al

However, many of its visible and internal signs are linked to a decline in cellular function and hormone production

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