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As Chun-Su Yuan, MD, PhD, the Cyrus Tang Professor of Anesthesia and Critical Care at the University of Chicago told UChicagoMedicine, Its also important to note that the long-term side effects of these drugs are not yet well-studied

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Keywords Salicylate Toxicology Source: aspirin or your local willow tree Mechanism of Action: Salicylates cause an uncoupling of oxidative phosphorylation Catabolism occurs secondary to the inhibition of ATP-dependent reactions with the following results: increased oxygen consumption,increased carbon dioxide production, accelerated activity of the glycolytic and lipolytic pathways, depletion of hepatic glycogen,hyperpyrexia Dosages: The usual daily dosage range for aspirin is two regular strength aspirin tablets (325 mg x 2 = 650 mg) every 4 hours (or 12 tablets/day)

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