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Pathway and gene set enrichment analysis was done using fgsea packages

[33] [34] These inactivating factors are furthermore regulated by different Non-coding RNAs: The sRNA NsiR4 interacts with the 5'UTR of the mRNA of the GS inactivating factor IF7 ( gifA mRNA) and reduces its expression

In humans, small intestinal epithelial cells convert Gln and glutamate to citrulline, which is then transported by the circulatory system to renal proximal tubular cells, where arginine is synthesized by arginine-succinate synthetase and arginine-succinate lyase in the urea cycle

These complexes reduce molecular oxygen (O) to superoxide anion (O 2 -) through the activity of nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH 2 )