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Although lipid profiles, including TC, TG, LDL-C, and HDL-C levels, did not significantly differ among EC- Slc7a11 -/- and Slc7a11 flox/flox littermates (Figure 5C), en face Oil-red O staining revealed a significant increase in atherosclerotic lesions in the aortas of EC- Slc7a11 -/- male and female mice as compared with Slc7a11 flox/flox littermates (Figure 5D)

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The Unpublished Phase I Trial: A Critical Look A pivotal point of discussion is the Phase I clinical trial for BPC-157 in patients with IBD, registered on ClinicalTrials.gov