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For example, PARP1 binds a DNA single strand break, then utilizes NAD + to ADP-ribosylate macromolecules in the vicinity, a signal for recruitment of DNA repair machinery 6

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The characterization of a thermostable and cambialistic superoxide dismutase from Thermus filiformis

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This multi-layered regulatory mechanism weakens the differentiation of naive T cells into anti-tumor Th1 cells while promoting their differentiation into pro-tumor Th2 cells