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Autoreactive CD8 + T cells in multiple sclerosis: A new target for therapy

A case-control study (50 domestic shorthair cats with a confirmed diagnosis of FISS and 100 disease-free matched controls) investigating a possible association between polymorphisms in the genomic sequence of the feline p53 gene and a predisposition to FISS, found a strong association between FISS and the presence of specific nucleotides at two of the polymorphic sites (Banerji et al., 2007)

Overall, second-line treatment was started in 26.7% (16/60) of patients in EBS group due to failure of the first-line therapy (adalimumab in 7/16, 43.8%

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