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Other reports have shown that LC has an antioxidant effect, can inhibit the production of reactive oxygen species, avoid sperm oxidative damage, and effectively maintain the normal physiological function of sperm (12,13)

Conversely, there is an increase in CD56 dim cells, which are predominantly cytotoxic [196,197,198]

Disclosures: Kyoko Fukuhara: Nothing to Disclose, Yuichi Tsuchiya: Nothing to Disclose, SHUNHEI YAMASHINA: Nothing to Disclose, Xingchen Liu: Nothing to Disclose, Kazuyoshi Kon: Nothing to Disclose, Akira Uchiyama: Nothing to Disclose, Reiko Yaginuma: Nothing to Disclose, Kei Ishizuka: Nothing to Disclose, Hiroyasu Nakano: Nothing to Disclose, Kenichi Ikejima: Nothing to Disclose 1993 TARGETING TEAD1 ACTIVE ISOFORM TO ALLEVIATE LIVER FIBROSIS IN PRIMARY SCLEROSING CHOLANGITIS Roi Isaac 1 Jinyue Wang 1 Sion Kang 1 Victoria Nguyen 1 Charles McWherter 2 Jerrold Olefsky 1 , 1 University of California, San Diego, 2 CymaBay Therapeutics Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, leading to progressive liver damage

*Correspondence: Min Liu, [email protected]