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A random search strategy with up to 1,000 evaluations was employed within each learner-specific parameter space, using AUC as the optimization criterion

GSSP can form either by direct reaction with reactive oxygen species (ROS) or by reaction with secondary products of oxidative stress such as GSSG (Dalle-Donne et al

When abnormal results are detected, the interpretation should include an overview of the results and their significance, quantitative results with age-appropriate reference ranges, a correlation to available clinical information, elements of differential diagnosis, recommendations for additional biochemical testing and in vitro confirmatory studies (e.g., enzymatic analysis, molecular analysis), and a phone number to reach the reporting laboratory with additional questions

This patient's lack of primary gastrointestinal malignancies and presence of a parafollicular cell neoplasm make a DNA mismatch repair gene mutation unlikely