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Metal NPs exhibit potent bactericidal activity by influencing bacterial viability via many mechanisms, including compromising membrane integrity by fusion and damage, inhibiting drug efflux pumps, obstructing electron transport, and denaturing proteins [191]

While a two-year clinical trial using 300 mg per day did not show major changes in nerve function, shorter studies lasting 3 to 12 weeks found that higher doses, up to 600 mg daily, improved symptoms in people with diabetic neuropathy

Allergen-induced substance P synthesis in large-diameter sensory neurons innervating the lungs