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If the ELISA is positive or equivocal (borderline), the lab proceeds to the second tier: a Western blot (Immunoblot) test

Diabetes 53 : S119S124 Broyer M, Tete MJ, Gubler MC 1987 Late symptoms in infantile cystinosis

274 ENDOG suppresses the mTORC1 pathway by interacting with 14-3-3, which releases TSC2

4.2 Cysteine and homocysteine in kidney diseases As evidenced by several studies, the kidneys play a pivotal role in the regulation of the methionine cycle, exerting a direct influence on alterations in the concentrations of homocysteine, cysteine, S-adenosylmethionine, S-adenosylhomocysteine, and the SAH/SAM ratio [56, 57]