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Our commitment to quality supports reproducible research outcomes across diverse experimental applications

10.1038/nri3430 32 KangE

Lu K, Li HY, Yang K, Wu JL, Cai XW, Zhou Y, et al

This system provides sequential therapeutic action: the DNA component acts as an early scavenger of damaging ROS, while the subsequently active aptamer competitively binds C5a, thereby inhibiting complement activation and downstream inflammatory amplification during later stages of IRI [68]