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Some people feel a boost in energy within hours, while for others, it builds gradually over a few days

The standard NHS regimen for treating deficiency involves loading doses followed by maintenance therapy, with frequency determined by the underlying cause and severity of deficiency

The human body cannot produce vitamin B12

Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition