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Integration of hiPSC technology with small-molecule high-throughput screening (HTS) facilitates the identification of novel pharmacotherapeutic agents, whereas transcriptomic profiling enables comprehensive gene expression analysis of patient-specific organoids

These data suggest that ghrelin may aid in two ways: (1) by amplifying the remaining dopaminergic signaling through the D1R-GHSR1a dimer, and (2) by providing neuroprotective effects that may aid in slowing the progression of further dopaminergic degeneration, which may be the result of GHSR signaling alone

used mass spectral fingerprinting, metabolomic analysis, and genetic sequencing to assess 71 maca samples from Peru and China, 39 commercial maca supplements from 11 different companies, 31 unprocessed maca tubers, and a maca non-tuber historical sample [68]

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