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In addition to the findings with ASMase knockout mice, which models the lysosomal storage disorder NiemannPick type A disease, inhibition of glucocerebrosidase in hepatocytes by conduritol -epoxide, a cellular model of Gaucher disease that exhibits lysosomal cholesterol accumulation sensitizes to APAP-induced cell death (Teratani et al., 2017)

The authors observed that arginine supplementation caused a significant enhancement of lymphocyte proliferative responses to the T-cell mitogen phytohemagglutinin after 35 days and led to significant increases in blood leucocyte phagocytic activity after both 14 and 35 days (173)

These patterns are consistent in Charlotte, and Wells Fargo underperformed peer banks in mortgage activity in census tracts where people of color make up the majority of the population (see Section II.B)