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Avoid combining directly with strong acids, low-pH exfoliating systems, strong oxidizers, or high levels of free metal chelators

Research investigations commonly explore the compound in experimental models examining: FOXO transcription factor signalling pathways Proteinprotein interaction dynamics Cellular senescence signalling networks Intracellular regulatory pathway modelling Molecular protein interaction research Comparative peptide interaction studies Cellular stress response signalling mechanisms Research Applications In controlled research environments, FOXO4-DRI may be utilised in experimental models designed to explore cellular regulatory pathways and protein interaction systems

10.1007/82_2016_508 28 JangS.KwonE-J.LeeJ

Mutants Glu435Ala and Asp437Ala, within the EDD sequence responsible for metal ion coordination, were found completely inactive in both luminescence and HRMS assays (Fig