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Aside from its impact on HDL and other plasma lipids, nicotinic acid has exhibited anti-atherosclerotic activities in cultured monocytes, macrophages, or vascular endothelial cells, by modulating inflammation and oxidative stress and regulating cell adhesion, migration, and differentiation (reviewed in 18)

The decline in smoking over the past two decades has been one of the great public health achievements of the 21st century, but worsening air pollution has offset many of the expected gains in general respiratory health

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Secondhand smoke refers to the smoke that comes from burning tobacco products such as cigarettes, cigars, or pipes, combined with the smoke exhaled by the smoker