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Atherosclerotic cardiovascular disease, or ASCVD, develops when cholesterol-rich ApoB-containing particles become retained in arterial walls and contribute to plaque formation

For sacral nerve stimulation (SNS), a posterior midline incision was performed, and a pair of electrodes (cardiac pacing wire, A&E Medical, Farmingdale, NJ) was placed around right sacral nerve (S3) behind the sacral foramen and fixed by a surgical knot 23 mm apart (oval cathode 23 mm in length in each electrode) and the dental cement was used to isolate the exposed wires from circumjacent tissues (Huang et al., 2019

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