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CD38 inhibitors may show short-term efficacy, but their long-term efficacy and potential issues of resistance must be evaluated

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Lumbar radicular pain can cause the following symptoms, which can radiate from your low back down the back of your leg below your knee to your calf and/or foot: Many conditions can irritate your spinal nerve roots in your low back and cause lumbar radiculopathy (sciatica), including: Advertisement Other conditions that may be treated with lumbar ESIs include: Epidural steroid injections are among the most common type of therapy for managing radicular pain

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