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doi: 10.1016/j.jaci.2019.12.910 137 EwingEKularLFernandesSJKarathanasisNLaganiVRuhrmannSet al

Overton, C

Many newly developed DUB inhibitors, such as Novartis's CSN5i-3 (102) or the already marketed drug pimozide (103), have been found to exhibit significant functions in the field of cancer therapy

Enrichment analysis of proteins whose abundance increased at least 2 times in therapy-induced secretomes from all cancer cell lines revealed a predominant association with splicing regulation (Fig