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Abstract Diabetic cardiomyopathy (DCM) is one of the crucial causes leading to heart failure and adverse outcomes in patients with diabetes mellitus

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In the benzisoselenazol-3(2 H )-one region of the NMR spectra measured in DMSO- d 6 , the proton H-4, H-5, H-6, and H-7 resonances of compound 123 were observed at: 7.857.94, 7.457.51, 7.527.78, and 8.058.12 ppm, respectively, and the carbon C=O, C-3, C-4, C-5, C-6, C-7 and CSe resonance generally were observed at 164.87166.08, 126.43128.53, 127.73128.22, 126.06126.52, 132.07133.01, 125.71126.07 and 138.50140.59 ppm, respectively, while the carbon atom of a phenyl substituent linked with heteroaromatic (PhC-1) resonance were observed at 119.7146.3 ppm, dependent on the substituents used