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10.1126/scitranslmed.aan8162 Sci

D., Miguel, B

The reason for this phenomenon may be that the LDL receptor-related proteins mainly mediate lipoprotein clearance by the liver when LDL receptors are absent, while the lack of apoE prevents the normal diet-induced increase of very-low-density lipoprotein (VLDL) production [58, 59]

Corroborating the results in animal models of T1D treated with GABA and GAD65-alum could clarify whether the peripheral immune responses resemble the islet microenvironment