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Therefore, we hypothesize that MKL-1 may influence cellular ferroptosis by participating in the regulation of system Xc-

This increased expression of miR-144, in turn, can potentially reduce the levels of mRNA expression of ZEB1 and ZEB2

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Similarly, Huangqi-Danshen decoction targets stearoyl-CoA desaturase 1 to inhibit cGAS-STING signaling, disrupting fibrotic cascades (Hong et al., 2018