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SAM-e (S-Adenosyl-Methionine) is a revolutionary dietary supplement that has been successfully used for nearly half a century to support positive mood and well-being, joint comfort, and healthy liver function

However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug

The means by which an RP determines authorization and access is out of scope for these guidelines

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