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This observation indicated that not only specific antibodies but independently also vaccination-induced CD8 T cells were able to contain rLCMV/LASV LIV C challenge viremia, such that assessing the antiviral efficacy of the former required depletion of the latter

Also, vitamin B12 deficiency tends to come on very slowly, so people often go through a long period of being mildly deficient

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Also, the cross-over design of the study may not be most appropriate to answer the study question given that cobalamin could be stored in the liver for a long time up to 2 to 3 years