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When researchers select GHRP-6 : models examining tissue cytoprotection that is not mediated through the GH axis, including cardiac ischaemia-reperfusion, hepatic fibrosis, and wound healing models

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rhGH triggered IGF1 changes in the hypothalamus, liver, and testes of immature rats IGF1 mediates GH-dependent and GH-independent anabolism and growth [41, 42]