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Description

H., Billeter, M., Holmgren, A

Inflammasomes Large cytoplasmic multiprotein complexes that sense microbial infections or danger molecules and initiate auto-proteolytic cleavage of caspase 1, and the subsequent processing and release of pro-inflammatory cytokines, namely interleukin-1 and IL-18

By reducing oxidative stress and generating inflammatory cytokines by multiple mechanisms, such drugs can likely work together to reduce the body's overall inflammatory burden