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Based on their findings, Kannan and colleagues hypothesized that the Na + -dependent GSH transporter may be operational for uphill transport of GSH while the Na + -independent GSH transporter may be operational bidirectionally and involved in GSH efflux [37]

Introduction Hypermobile EhlersDanlos Syndrome (hEDS) stands out as the most common form of EDS, yet it remains frequently underdiagnosed due to its diverse clinical manifestations and the absence of specific genetic markers [1,2]