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Initially designed to enhance insulin sensitivity and regulate hyperglycemia, metformin exhibits a range of pleiotropic effects that may be particularly advantageous in addressing various inflammatory and metabolic disorders, including OA (108110)

Studies show that oral L-Carnitine supplementation can: Decrease fat mass Preserve muscle during exercise Reduce muscle fatigue Research indicates that Carnitine also helps determine whether the body uses muscle tissues, carbohydrates, or fat for energy

Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients

Carnitine is only found in limited quantities in plant protein