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Endocrinology (2014) 155(4):128090

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Anti-Inflammatory and Cytokine Regulation BPC-157 downregulates pro-inflammatory mediators including: Tumor Necrosis Factor-Alpha (TNF-) Interleukin-1 Beta (IL-1) Interleukin-6 (IL-6) Leukotrienes key drivers of pain and inflammation in arthritis and tendinopathy Growth Hormone Receptor Upregulation Emerging research suggests BPC-157 increases growth hormone receptor density in injured tissues, amplifying the natural repair signals that decline with age or chronic inflammation