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2) What kind of protective functions will play roles in protecting the microorganisms against the chlorination

The main toxicity provoked is acute liver damage, which is mechanistically provoked by the aberrant adduction of the toxic metabolite N-acetyl p-benzoquinone imine (NAPQI) to cysteinyl residues of key liver proteins [105]

Therefore, the design of combination regimens must be informed not only by the metabolic crosstalk (e.g., via GSH depletion) but also by real-time immune monitoring of the TME

Front Plant Sci 12:646221 Lini I, amec D, Grz J, Vuji Bok V, Strnad M, Salopek-Sondi B (2019) Involvement of phenolic acids in short-term adaptation to salinity stress is species-specific among Brassicaceae