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10.1016/j.tox.2005.06.014 Toxicology

Hou C, Yin F, Wang S, Zhao A, Li Y, Liu Y

In conclusion, probiotics represent a valuable and biologically plausible therapeutic approach to reinforcing the intestinal TJ barrier and mitigating barrier-related GI pathologies

When small intestinal mucosa atrophies, it causes an increase in epithelial permeability and compromised tight junctions, which can lead to translocation of bacteria