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Contrary to prior conclusions from preclinical models and retrospective studies suggesting that NAFLD-related HCC might resist immune checkpoint inhibitors (ICIs), this patient-level analysis found no significant differences in overall response rate (ORR), progression-free survival (PFS), or overall survival (OS) across liver disease etiologies, challenging earlier assumptions about NAFLDs impact on ICI outcomes (2225)

As mentioned previously, incorporating an adequate amount of polyphenols into our diet or considering polyphenol supplementation can be highly beneficial for maintaining our health, preventing and helping our body to fight against oxidative stress [161]

Synbiotics can also influence positively metabolic parameters such as lipid profiles, blood sugar levels, and body weight

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