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While MOTS-c acts as a signaling molecule, SS-31 works to repair the inner mitochondrial membrane, offering a complementary approach to cellular rejuvenation.

In 2019, in the 'Journal of cosmetic dermatology,' a group of researchers studied the clinical effects of glutathione on skin color and related skin conditions

Thus, the association of Shank3 with mitochondrial proteins and processes, including the mitochondrial ETC activity, has been established, although the mechanisms connecting SHANKs and mitochondria at the excitatory synapses remain unknown