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Description

Your cells produce energy in structures called mitochondria

Oncotarget 8 (70), 115270115279

doi: 10.1016/s1369-5274(00)00162-4 29 BanksMGrahamDJansenMGotodaTCodaSdi PietroMet al

In summary, F16 acts as a DLC that can be targeted to cluster in the mitochondrial matrix of tumor cells, and its conjugate can depolarize m, increase Ros to attack mtDNA to kill cancer cells, and overcome multiple drug resistance