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Upon interaction with GSH, IR806-PDA is converted into IR806-S-NH, resulting in a spectral shift (from 680 to 820 nm) and generating ratiometric photoacoustic signals that correlate with GSH levels

The mitochondrial DNA encodes for all the RNA involved in protein synthesis in the matrix but also for 13 proteins that are subunits of the ETC complexes: seven subunits in Complex I, one in Complex III, three in Complex IV, and one in the ATP synthase (sometimes called complex V)

10.1016/j.freeradbiomed.2021.06.012 215 TangB.ZhuJ.ZhangB.WuF.WangY.WengQ.et al (2020b)

Macrocyclic lactone Rapamycin, a macrocyclic lactone isolated from Streptomyces hygroscopicus , is known for its immunosuppressive and antimicrobial properties due to its ability to inhibit the mTOR pathway, thereby promoting autophagy [63]