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Description

3.2.4 Nrf2 pathway Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor that regulates the expression of a wide array of antioxidant and cytoprotective genes

RochdiCOuadrhiriMAllaiLBellajdelIMamriSTaheriHet al

doi: 10.1002/glia.10314

This process is achieved by regulating the expression levels of -catenin and its downstream targets, including CyclinD1, MMP7, c-Myc, c-Jun, AXIN2 and glutamine synthase [61]