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While senescence functions as a defense mechanism against the propagation of damaged cells and thus prevent the development of cancer and other diseases, it also contributes to the aging process when senescent cells accumulate over time in tissues

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PubMed Sikiric, P., Separovic, J., Anic, T., Buljat, G., Mikus, D., Seiwerth, S., Grabarevic, Z., Stancic-Rokotov, D., Pigac, B., Hanzevacki, M., Marovic, A., Rucman, R., Petek, M., Ziger, T., Sebecic, B., Zoricic, I., Turkovic, B., Aralica, G., Perovic, D., Duplancic, B., Lovric-Bencic, M., & Rotkvic, I

These protective functions are likely rewired in many neurological and neurodegenerative disorders in the adult