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The authors defined COVID-19 disease severity as either moderate or mild using metrics from the National Early Warning Score methodology, where respiratory rate, oxygen saturation, oxygen supplement, body temperature, systolic blood pressure, heart rate, and consciousness were used as evaluating criteria 49,96

PMID: 9587028

On the other hand, iron overload induced ferroptosis in foam cells which led to plaque instability, and ferroptosis in foam cells increased IL-1 and IL-8 expression, promoting inflammatory responses (Su et al., 2021)

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