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After the blood collection, mice were flushed with ice-cold PBS to remove residual blood

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Several of these chaperones are colocalized or associated with the PD related proteins, E3-ubiquitin ligase (E 6.3.2.19), parkin, -synuclein and the dopamine transporter (DAT) [119]

Its clinical significance lies in its ability to detect early renal involvement, predict systemic vascular stress, and reflect subclinical target organ damage across multiple systems