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10.1517/14712598.2015.1011617 15 GouldL.AbadirP.BremH.CarterM.Conner-KerrT.DavidsonJ.et al (2015)

F., Jin X., Zhang Y., Xu Q., Ding H

Chromium and signaling pathways In a study of chromium(VI)-induced hepatotoxicity, hexavalent chromium was reported to activate Kupffer cells, which can release proinflammatory cytokines such as the tumor necrosis factor TNF- and the interleukins IL-6 and IL-1 and activate the nuclear factor kappa B (NF-B) signaling pathways (p-IKK/ and p-p65) (Shen et al