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Sirtuin 2 (SIRT2)-P53 signaling pathway The SIRT2-p53 pathway exerts neuroprotective effects by modulating GPX4 and SCL7A11, inhibiting the occurrence of ferroptosis (100)

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Antimicrobial prophylaxis is indicated in patients undergoing dental procedures who have: a) Unrepaired cyanotic CHD including those with palliative shunts and conduits, b) Completely repaired CHD with a prosthetic material or device during the first 6 months after the procedure c) Repaired CHD with a residual defect Antibiotics are NOT recommended for patients who have procedures involving the reproductive, urinary or gastrointestinal tract

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