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134 These observations underscore the complex and context-dependent effects of ERAD in adipose tissue, linking local proteostasis to systemic lipid homeostasis

10.1016/S0143-4160(03)00141-6 Cell Calcium 16 AydemirO.NazroluM.CelebiS.YlmazT.KknerA

The clearance of senescent liver cells triggered by DMC is synergistically mediated by the activation of ferritinophagy and the inhibition of ferrochelatase (FECH), an essential enzyme for heme biosynthesis by inserting a ferrous ion into protoporphyrin IX (134)