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We found that wild-type MZB were more susceptible to Gclc inhibition as shown by a stronger BSO concentration-dependent decrease in viability and total immunoglobulin secretion in the culture supernatants when compared to FoB (Fig

Gonzalez-Leon A, Schultz IR, Xu G, et al

S.ChenB.GuoL

As NUPR1 expression was at best marginally reduced in IPF-derived phBECs in our study, the increased susceptibility to NUPR1 inhibition likely reflects more nuanced mechanisms