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To function correctly, they need high levels of glutathione

The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients

The select targets were related to metabolic pathways ( Cpt1a , Cpt1c and Pgc1 ), oxidative stress ( Nox2 ) and markers of reactive microglia/macrophage/astrocyte ( Iba1 , Cd68 and Gfap ) (Fig