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Antioxidant mechanisms are regulated by nuclear factor erythroid 2 like 2 (NFE2L2/NRF2) and membrane repair during ferroptosis involves endosomal sorting complexes required for transport (ESCRT-III) activation [74]

In dermatology practice, it is mainly used in the treatment of dermatocompulsions and pseudoporphyria.8,9 In a non-randomized trial with 30 Egyptian women, one group (n = 10) received oral glutathione 500 mg/day, while another used topical glutathione 2%, and a third used placebo for four weeks, always associated with SPF 30 sunscreen