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Ascorbic acid and rates of cognitive decline in Alzheimer's disease

The interplay among multiple pathobiological pathways, such as the persistence of viral reservoirs, direct SARS-CoV-2-related tissue damage, dysbiosis, ongoing inflammation, autoimmunity and microthrombi phenomena, has been proposed as the main driver of Long COVID [9, 10]

To date, more than 600 distinct PTM types have been identified, including phosphorylation, acetylation, ubiquitination, sumoylation, methylation, glycosylation, palmitoylation and succinylation (Walsh et al., 2005)

Two key enzymes that control histone modifications are histone methyltransferases and deacetylases, and dysregulation of these enzymes may play a role in HT pathogenesis (Pu And Zhang 2024)