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Other Medications or Substances: Some drugs interact with trazodone or compete for the same metabolic pathways, potentially delaying its elimination

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In a controlled study by Samsom and colleagues, healthy subjects given pramlintide showed gastric-emptying half-times that lengthened from about 112 minutes on placebo to roughly 169 minutes at 30 g and 177 minutes at 60 g a delay of more than an hour at the higher dose